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2017•Unpublished venueRequires access

Antioxidant and Cytotoxic Activities and Phytochemical Screening of Beligo (Benincasa Hispida Thunb. Cogn) Seeds Extract

Muhammad Salsabeela Rusdi, Novita Sismasari, Agustiana Agustiana, Sitti Fauziah Noer, Tahirah Hasan

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Abstract

The aims of this research were to determine the antioxidant and cytotoxic activities and phytochemical screening of Beligo (Benincasa hispida Thunb. Cogn) seeds extract. The extraction of Beligo seeds by maceration using ethanol 96%. Antioxidant activity was determined by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical. The IC50 value for DPPH assay was 54,987 ppm. The cytotoxic activity was assessed by using brine shrimp lethality test (BSLT). The LC50 values of the tested samples was 4,666 ppm. Phytochemical screening showed positive results for flavonoids, terpenoids, and alkaloids.

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What this paper is about

The aims of this research were to determine the antioxidant and cytotoxic activities and phytochemical screening of Beligo (Benincasa hispida Thunb. Cogn) seeds extract. The extraction of Beligo seeds by maceration using ethanol 96%. Antioxidant activity was determined by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical. The IC50 value for DPPH assay was 54,987 ppm. The cytotoxic activity was assessed by using brine shrimp lethality test (BSLT). The LC50 values of the tested samples was 4,666 ppm. Phytochemical screening showed positive results for flavonoids, terpenoids, and alkaloids.

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Available abstract

The aims of this research were to determine the antioxidant and cytotoxic activities and phytochemical screening of Beligo (Benincasa hispida Thunb. Cogn) seeds extract. The extraction of Beligo seeds by maceration using ethanol 96%. Antioxidant activity was determined by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical. The IC50 value for DPPH assay was 54,987 ppm. The cytotoxic activity was assessed by using brine shrimp lethality test (BSLT). The LC50 values of the tested samples was 4,666 ppm. Phytochemical screening showed positive results for flavonoids, terpenoids, and alkaloids.

Key concepts: Phytochemical, DPPH, Brine shrimp, Traditional medicine, Maceration (sewage), Antioxidant, Terpenoid, Chemistry

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