2018Journal of NeuroscienceOpen access

A Therapeutic Link between Astrogliosis and Remyelination in a Mouse Model of Multiple Sclerosis

Craig S. Pearson

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Abstract

Injuries to the mammalian CNS often provoke astrogliosis, a process in which reactive astrocytes surround the site of injury to restrict tissue damage ([Voskuhl et al., 2009][1]; [Hamby and Sofroniew, 2010][2]). Formation of the glial scar has historically been viewed as a short-term solution that

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Injuries to the mammalian CNS often provoke astrogliosis, a process in which reactive astrocytes surround the site of injury to restrict tissue damage ([Voskuhl et al., 2009][1]; [Hamby and Sofroniew, 2010][2]). Formation of the glial scar has historically been viewed as a short-term solution that

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Available abstract

Injuries to the mammalian CNS often provoke astrogliosis, a process in which reactive astrocytes surround the site of injury to restrict tissue damage ([Voskuhl et al., 2009][1]; [Hamby and Sofroniew, 2010][2]). Formation of the glial scar has historically been viewed as a short-term solution that

Key concepts: Astrogliosis, Remyelination, Neuroscience, Multiple sclerosis, Glial scar, Gliosis, Astrocyte, Medicine

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