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2017•Hong Kong bulletin on rheumatic diseasesOpen access

Successful treatment of macrophage activation syndrome complicating adult-onset Still’s disease with tocilizumab: a case report

Ho So, T. L. V. Wong, Hin Ting Pang, Weng Nga Lao, M.-L. Yip

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Abstract

Abstract We report a case of 50-year-old female patient with adult-onset Still’s disease (AOSD) complicated by macrophage-activation syndrome (MAS). After initial control of the disease with high-dose parenteral corticosteroids, tocilizumab (TCZ) therapy aided in maintaining the remission with rapid tapering of steroid dose. TCZ may be useful for MAS complicating AOSD.

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What this paper is about

Abstract We report a case of 50-year-old female patient with adult-onset Still’s disease (AOSD) complicated by macrophage-activation syndrome (MAS). After initial control of the disease with high-dose parenteral corticosteroids, tocilizumab (TCZ) therapy aided in maintaining the remission with rapid tapering of steroid dose. TCZ may be useful for MAS complicating AOSD.

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Available abstract

Abstract We report a case of 50-year-old female patient with adult-onset Still’s disease (AOSD) complicated by macrophage-activation syndrome (MAS). After initial control of the disease with high-dose parenteral corticosteroids, tocilizumab (TCZ) therapy aided in maintaining the remission with rapid tapering of steroid dose. TCZ may be useful for MAS complicating AOSD.

Key concepts: Tocilizumab, Macrophage activation syndrome, Adult-onset Still's disease, Medicine, Disease, Internal medicine, Pediatrics, Immunology

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