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2017•Journal of Clinical EpigeneticsOpen access

Challenges in the Analysis of Micro RNAs from Liquid Biopsy as Epigenetic Biomarkers in Clinical Samples

José Luis García Giménez, Gisselle Perez Machado, Eva Garcia Lopez, Dayme Gonzalez Rodriguez, Salvador Mena Molla

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Abstract

Additionally, it has been demonstrated that miRNAs are stable in archived serum samples frozen at -25°C for at least 40 years [9] and at -20°C for at least 2-4 years [10].Because of these properties, miRNAs hold great promise as minimally invasive diagnostic and prognostic biomarkers.

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Additionally, it has been demonstrated that miRNAs are stable in archived serum samples frozen at -25°C for at least 40 years [9] and at -20°C for at least 2-4 years [10].Because of these properties, miRNAs hold great promise as minimally invasive diagnostic and prognostic biomarkers.

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Available abstract

Additionally, it has been demonstrated that miRNAs are stable in archived serum samples frozen at -25°C for at least 40 years [9] and at -20°C for at least 2-4 years [10].Because of these properties, miRNAs hold great promise as minimally invasive diagnostic and prognostic biomarkers.

Key concepts: Epigenetics, Liquid biopsy, Biomarker, Computational biology, microRNA, Small nucleolar RNA, DNA methylation, Biology

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