2017•The OncologistOpen access

High-Dose Mitotane-Induced Encephalopathy in the Treatment of Adrenocortical Carcinoma

Elise Pape, Catherine Féliu, Mélissa Yelehe‐Okouma, Natacha Colling, Zoubir Djerada, Nicolas Gambier, G. Weryha, Julien Scala‐Bertola

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Abstract

In response to the recently published article by Reidy-Lagunes et al., which deals with clinical response to mitotane treatment in advanced adrenocortical carcinoma and the toxicity associated with this treatment, this letter to the editor reports a case of mitotane-induced encephalopathy during a high-dose mitotane treatment in adrenocortical carcinoma.

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Key concepts: Mitotane, Adrenocortical carcinoma, Medicine, Toxicity, Carcinoma, Encephalopathy, Oncology, Internal medicine