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2017•DEStech Transactions on Biology and HealthOpen access

Antioxidant and Anti-inflammatory Activities of Extracts from Callicarpa longissima

Yuxia Fu, De-Sheng Ning, Zheng‐Hong Pan

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Abstract

This work aimed to evaluated the antioxidant and anti-inflammatory activities of extracts from Callicarpa longissima. The antioxidant activity was determined by DPPH method , the results indicated that the dichloromethane extract, ethyl acetate extract and n-butanol extract showed the strongest antioxidant capacity with the IC50 values of 12.39 μg/mL, 10.51μg/mL and 11.36 μg/mL. The anti-inflammatory activities was measured by NO assay, which showed the dichloromethane extract and ethyl acetate extract possess a significantly NO inhibition with the IC50 values of 8.75 μg/mL and 7.25 μg/mL. The results provide theoretical basis for development and utilization of this plant.

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What this paper is about

This work aimed to evaluated the antioxidant and anti-inflammatory activities of extracts from Callicarpa longissima. The antioxidant activity was determined by DPPH method , the results indicated that the dichloromethane extract, ethyl acetate extract and n-butanol extract showed the strongest antioxidant capacity with the IC50 values of 12.39 μg/mL, 10.51μg/mL and 11.36 μg/mL. The anti-inflammatory activities was measured by NO assay, which showed the dichloromethane extract and ethyl acetate extract possess a significantly NO inhibition with the IC50 values of 8.75 μg/mL and 7.25 μg/mL. The results provide theoretical basis for development and utilization of this plant.

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Available abstract

This work aimed to evaluated the antioxidant and anti-inflammatory activities of extracts from Callicarpa longissima. The antioxidant activity was determined by DPPH method , the results indicated that the dichloromethane extract, ethyl acetate extract and n-butanol extract showed the strongest antioxidant capacity with the IC50 values of 12.39 μg/mL, 10.51μg/mL and 11.36 μg/mL. The anti-inflammatory activities was measured by NO assay, which showed the dichloromethane extract and ethyl acetate extract possess a significantly NO inhibition with the IC50 values of 8.75 μg/mL and 7.25 μg/mL. The results provide theoretical basis for development and utilization of this plant.

Key concepts: Ethyl acetate, Antioxidant, Dichloromethane, DPPH, Chemistry, Traditional medicine, Anti-inflammatory, IC50

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