2017JAAPARequires access

Amiodarone-induced pulmonary toxicity

Rebecca Colby, Holly L. Geyer

Open publisher page 29 citations

Abstract

Amiodarone is widely used to prevent ventricular and supraventricular dysrhythmias but has a number of toxicities. One of the most devastating adverse reactions to this drug is pulmonary toxicity, which can present in a myriad of different ways. Toxicity is difficult to diagnose because many of its features also are seen in nontoxic patients. This article reviews the pathophysiology, presentation, diagnosis, and treatment of amiodarone-induced pulmonary toxicity.

About this research paper

What this paper is about

Amiodarone is widely used to prevent ventricular and supraventricular dysrhythmias but has a number of toxicities. One of the most devastating adverse reactions to this drug is pulmonary toxicity, which can present in a myriad of different ways. Toxicity is difficult to diagnose because many of its features also are seen in nontoxic patients. This article reviews the pathophysiology, presentation, diagnosis, and treatment of amiodarone-induced pulmonary toxicity.

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OpenAlex reports 29 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Amiodarone is widely used to prevent ventricular and supraventricular dysrhythmias but has a number of toxicities. One of the most devastating adverse reactions to this drug is pulmonary toxicity, which can present in a myriad of different ways. Toxicity is difficult to diagnose because many of its features also are seen in nontoxic patients. This article reviews the pathophysiology, presentation, diagnosis, and treatment of amiodarone-induced pulmonary toxicity.

Key concepts: Amiodarone, Pulmonary toxicity, Toxicity, Medicine, Adverse effect, Presentation (obstetrics), Drug, Drug toxicity

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