2017Translational MedicineOpen access

CURRENT TREATMENT OF TWIN-TO-TWIN TRANSFUSION SYNDROME

F. A. Ovsyannikov, А. N. Romanovsky

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Abstract

Twin-to-twin transfusion syndrome – severe specific complication of monochorionic pregancy, which occurs in 10—15% monochorionic twins. The object of this paper is describing current treatment modalities of twin-totwin transfusion syndrome. Perinatal loss in case of conservative approach in twin-to-twin transfusion syndrome is more than 95%. Fetoscopic laser coagulation, amnioreduction, selective fetocide and preganancy termination are the current atreatment modalities of twin-to-twin transfusion syndrome. Fetoscopic laser coagulation is considered the most effective approach with highest rates of livebirth and the lowest maternal risks. In I stage twin-to-twin transfusion syndrome transabdominal amnioreductions can be effective, leading to resolving the disease. Intrauterine fetal surgery is the treatment of choice, preventing future morbidity in childhood and adolescence.

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Twin-to-twin transfusion syndrome – severe specific complication of monochorionic pregancy, which occurs in 10—15% monochorionic twins. The object of this paper is describing current treatment modalities of twin-totwin transfusion syndrome. Perinatal loss in case of conservative approach in twin-to-twin transfusion syndrome is more than 95%. Fetoscopic laser coagulation, amnioreduction, selective fetocide and preganancy termination are the current atreatment modalities of twin-to-twin transfusion syndrome. Fetoscopic laser coagulation is considered the most effective approach with highest rates of livebirth and the lowest maternal risks. In I stage twin-to-twin transfusion syndrome transabdominal amnioreductions can be effective, leading to resolving the disease. Intrauterine fetal surgery is the treatment of choice, preventing future morbidity in childhood and adolescence.

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Available abstract

Twin-to-twin transfusion syndrome – severe specific complication of monochorionic pregancy, which occurs in 10—15% monochorionic twins. The object of this paper is describing current treatment modalities of twin-totwin transfusion syndrome. Perinatal loss in case of conservative approach in twin-to-twin transfusion syndrome is more than 95%. Fetoscopic laser coagulation, amnioreduction, selective fetocide and preganancy termination are the current atreatment modalities of twin-to-twin transfusion syndrome. Fetoscopic laser coagulation is considered the most effective approach with highest rates of livebirth and the lowest maternal risks. In I stage twin-to-twin transfusion syndrome transabdominal amnioreductions can be effective, leading to resolving the disease. Intrauterine fetal surgery is the treatment of choice, preventing future morbidity in childhood and adolescence.

Key concepts: Twin Twin Transfusion Syndrome, Medicine, Twin-to-twin transfusion syndrome, Fetoscopy, Laser coagulation, Monochorionic twins, Complication, Laser surgery

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