2017European Heart JournalRequires access

P6226Differences in markers of cardiovascular prognosis between patients with ST segment elevation and non ST segment elevation myocardial infarction

George A. Lazaros, Konstantinos Dimitriadis, Dimitris Tsiachris, Alexios S. Antonopoulos, Athanasios Kordalis, Charalampos Vlachopoulos, Christina A. Chrysohoou, Costas P. Tsioufis, Dimitris Tousoulis

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Abstract

Background/Introduction: A variety of clinical parameters and biomarkers have been investigated in patients with acute myocardial infarction (MI) as predictors of future cardiovascular events. However, there are scarce data on the differences regarding these prognosticators between ST segment elevation MI (STEMI) and non ST segment elevation MI (NSTEMI) patients. Purpose: The aim of the present study was to identify the adverse prognostic markers in patients with STEMI and NSTEMI. Methods: The study population consisted of 522 consecutive patients admitted to the Coronary Care Unit of our institution with the diagnosis of MI (304 with STEMI and 218 with NSTEMI) within 12 hours of symptoms' onset. On admission, all patients underwent echocardiographic examination and fasting blood sample was obtained for the measurement of brain natriuretic peptide (BNP), white blood count, high sensitivity C-reactive protein, troponin I, plasma glucose and creatinine. Moreover, all patients included underwent coronary arteriography and as clinically indicated. The primary endpoint was the composite of MI, stroke and death during 1-year follow-up period.

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Background/Introduction: A variety of clinical parameters and biomarkers have been investigated in patients with acute myocardial infarction (MI) as predictors of future cardiovascular events. However, there are scarce data on the differences regarding these prognosticators between ST segment elevation MI (STEMI) and non ST segment elevation MI (NSTEMI) patients. Purpose: The aim of the present study was to identify the adverse prognostic markers in patients with STEMI and NSTEMI. Methods: The study population consisted of 522 consecutive patients admitted to the Coronary Care Unit of our institution with the diagnosis of MI (304 with STEMI and 218 with NSTEMI) within 12 hours of symptoms' onset. On admission, all patients underwent echocardiographic examination and fasting blood sample was obtained for the measurement of brain natriuretic peptide (BNP), white blood count, high sensitivity C-reactive protein, troponin I, plasma glucose and creatinine. Moreover, all patients included underwent coronary arteriography and as clinically indicated. The primary endpoint was the composite of MI, stroke and death during 1-year follow-up period.

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Available abstract

Background/Introduction: A variety of clinical parameters and biomarkers have been investigated in patients with acute myocardial infarction (MI) as predictors of future cardiovascular events. However, there are scarce data on the differences regarding these prognosticators between ST segment elevation MI (STEMI) and non ST segment elevation MI (NSTEMI) patients. Purpose: The aim of the present study was to identify the adverse prognostic markers in patients with STEMI and NSTEMI. Methods: The study population consisted of 522 consecutive patients admitted to the Coronary Care Unit of our institution with the diagnosis of MI (304 with STEMI and 218 with NSTEMI) within 12 hours of symptoms' onset. On admission, all patients underwent echocardiographic examination and fasting blood sample was obtained for the measurement of brain natriuretic peptide (BNP), white blood count, high sensitivity C-reactive protein, troponin I, plasma glucose and creatinine. Moreover, all patients included underwent coronary arteriography and as clinically indicated. The primary endpoint was the composite of MI, stroke and death during 1-year follow-up period.

Key concepts: Medicine, Elevation (ballistics), ST segment, Internal medicine, Myocardial infarction, Cardiology, Acute ST segment elevation myocardial infarction, Percutaneous coronary intervention

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