2017•NatureOpen access

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

Loren M. Lasko, Clarissa G. Jakob, Rohinton P. Edalji, Wei Qiu, Debra Montgomery, Enrico L. DiGiammarino, T. Matt Hansen, Roberto M. Risi, Robin R. Frey, Vlasios Manaves, Bailin Shaw, Mikkel A. Algire, Paul Hessler, Lloyd T. Lam, Tamar Uziel, Emily J. Faivre, Debra C. Ferguson, Fritz G. Buchanan, Ruth L. Martin, Maricel Torrent, Gary Gene Chiang, Kannan R. Karukurichi, J. William Langston, Brian Tate Weinert, Chunaram Choudhary, Peter de Vries, Arthur F. Kluge, Michael A. Patane, John H. Van Drie, Ce Wang, David J. McElligott, Ed Kesicki, Ronen Marmorstein, Chaohong C. Sun, Philip A. Cole, Saul H. Rosenberg, Michael R. Michaelides, Albert Lai, Kenneth D. Bromberg

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Key concepts: Lineage (genetic), Computational biology, Drug discovery, Chemistry, Biology, Genetics, Bioinformatics, Gene