2017International Journal of Drug Research and TechnologyRequires access

A STUDY ON ANTIOXIDANT ACTIVITY OF FRUIT EXTRACTS OF COCCINIA GRANDIS L.VOIGT.

Shreenivas R. Deshpande, M. J. Patil, Kusum Parmar, Shubhangi Daswadkar, R B Khodade

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Abstract

The aim of the present study was investigating the antioxidant activity of the methanolic extract of the fruit of Coccinia grandis L. Voigt. (Cucurbitaceae). The antioxidant activity of the fruit has been evaluated by using three in vitro assays and was compared to standard antioxidant, Butylated hydroxyanisole (BHA). All the fractions showed effective H-donor activity, reducing power, free radical scavenging activity. The antioxidant property depends upon concentration and increased with increasing amount of the fractions. The free radical scavenging and antioxidant activities may be attributed to the presence of flavonoids present in the fractions. The results obtained in the present study indicate that the fruit of Coccinia grandis is a potential source of natural antioxidant.

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What this paper is about

The aim of the present study was investigating the antioxidant activity of the methanolic extract of the fruit of Coccinia grandis L. Voigt. (Cucurbitaceae). The antioxidant activity of the fruit has been evaluated by using three in vitro assays and was compared to standard antioxidant, Butylated hydroxyanisole (BHA). All the fractions showed effective H-donor activity, reducing power, free radical scavenging activity. The antioxidant property depends upon concentration and increased with increasing amount of the fractions. The free radical scavenging and antioxidant activities may be attributed to the presence of flavonoids present in the fractions. The results obtained in the present study indicate that the fruit of Coccinia grandis is a potential source of natural antioxidant.

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Available abstract

The aim of the present study was investigating the antioxidant activity of the methanolic extract of the fruit of Coccinia grandis L. Voigt. (Cucurbitaceae). The antioxidant activity of the fruit has been evaluated by using three in vitro assays and was compared to standard antioxidant, Butylated hydroxyanisole (BHA). All the fractions showed effective H-donor activity, reducing power, free radical scavenging activity. The antioxidant property depends upon concentration and increased with increasing amount of the fractions. The free radical scavenging and antioxidant activities may be attributed to the presence of flavonoids present in the fractions. The results obtained in the present study indicate that the fruit of Coccinia grandis is a potential source of natural antioxidant.

Key concepts: Butylated hydroxyanisole, Antioxidant, Chemistry, Food science, Scavenging, Traditional medicine, Botany, Biology

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