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1978•Indian Journal of Dermatology Venereology and LeprologyRequires access

Dapsone Responsive Pemphigus

VL Rege, Sehgal Vn, M. F. Mascarenhas

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Abstract

A 45 year old female diagnosed clinically ,and histopathologically as a case of pemhigus responded well to prednisolone initially. The exacerbation of the condition on withdrawal of prednisolone could not be controlled even with sustained high dosage of prednisolone which led to multiple side effects. Dapsone in the dosage of 100 mg per day controlled the disease. The control of pemphigus in the patient by dapsone was further confirmed by withdrawal and reinstitution of the drug.

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What this paper is about

A 45 year old female diagnosed clinically ,and histopathologically as a case of pemhigus responded well to prednisolone initially. The exacerbation of the condition on withdrawal of prednisolone could not be controlled even with sustained high dosage of prednisolone which led to multiple side effects. Dapsone in the dosage of 100 mg per day controlled the disease. The control of pemphigus in the patient by dapsone was further confirmed by withdrawal and reinstitution of the drug.

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Available abstract

A 45 year old female diagnosed clinically ,and histopathologically as a case of pemhigus responded well to prednisolone initially. The exacerbation of the condition on withdrawal of prednisolone could not be controlled even with sustained high dosage of prednisolone which led to multiple side effects. Dapsone in the dosage of 100 mg per day controlled the disease. The control of pemphigus in the patient by dapsone was further confirmed by withdrawal and reinstitution of the drug.

Key concepts: Dapsone, Prednisolone, Exacerbation, Medicine, Pemphigus, Drug, Dermatology, Pharmacology

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