[PP.11.12] THE STUDY OF SINUS TACHYCARDIA IN PATIENTS WITH HYPERTENSION ASSOCIATED WITH ASTHMA

Objective: To study the frequency of sinus tachycardia in patients with AH associated with asthma. Design and method: 91 patients with mild and the average degree (1,2 degree) of AH, associated with asthma of varying degrees in the stage of control, were involved in the study. Of them, 26 patients (29%) with AH with asthma of mild severity – group I, 34 (37%) with asthma of the average severity- group II, 31 (34%) - with asthma of severe degree- group III. A group IV of 30 patients with AH 1,2 degree and a group V of 32 patients with separate BA were taken for a comparative analysis. All patients received the controller medication to asthma by inhaled glucocorticosteroids (IGCS) and β2-agonists short action. There was treatment of AH with tablet of indapamide 2.5 mg, and patients observed the recommendations about non- treatment AH therapy. Holter monitor ECG (HM-EKG) on GE SEER MC Marquette Medical System (USA) was performed to all subjects. Results: The sinus tachycardia was revealed in patients group I -12% of cases, group II-18%, and in group III- 58% of cases. In patients of group IV the sinus tachycardia was detected in 10%, in group V-28%. The significant difference was between I and III groups (p = 0.002), between the groups V and III (p = 0.01), between the results of groups IV and III (p = 0.001). Conclusions: An increase in the number of patients with AH, associated with asthma, with sinus tachycardia was revealed while bronchial obstruction progression, so that as confounding factor on influence of cardiovascular and respiratory pathology against each other.