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2011•Indo Global Journal of Pharmaceutical SciencesOpen access

A Review on Buccal Mucoadhesive Drug Delivery Systems

Roychowdhury Santanu, R. C. Gupta, Sourav Saha

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Abstract

Buccal mucosa is the preferred site for both systemic and local drug action. The mucosa has a rich blood supply and it relatively permeable. In this review article the advantages and limitations related to the buccal drug delivery has also been discussed. In buccal drug delivery systems mucoadhesion is the key element so various mucoadhesive polymers have been utilized in different dosages form. Various bioadhesive dosages form such as Chewing gum, tablets, Patches, Hydrogel, Thiolated tablets are discussed in this review article. Lastly the absorption/permeation study and different dissolution testing methods for bioadhesive dosages forms have also been discussed. © 2011 IGJPS. All rights reserved.

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Buccal mucosa is the preferred site for both systemic and local drug action. The mucosa has a rich blood supply and it relatively permeable. In this review article the advantages and limitations related to the buccal drug delivery has also been discussed. In buccal drug delivery systems mucoadhesion is the key element so various mucoadhesive polymers have been utilized in different dosages form. Various bioadhesive dosages form such as Chewing gum, tablets, Patches, Hydrogel, Thiolated tablets are discussed in this review article. Lastly the absorption/permeation study and different dissolution testing methods for bioadhesive dosages forms have also been discussed. © 2011 IGJPS. All rights reserved.

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Available abstract

Buccal mucosa is the preferred site for both systemic and local drug action. The mucosa has a rich blood supply and it relatively permeable. In this review article the advantages and limitations related to the buccal drug delivery has also been discussed. In buccal drug delivery systems mucoadhesion is the key element so various mucoadhesive polymers have been utilized in different dosages form. Various bioadhesive dosages form such as Chewing gum, tablets, Patches, Hydrogel, Thiolated tablets are discussed in this review article. Lastly the absorption/permeation study and different dissolution testing methods for bioadhesive dosages forms have also been discussed. © 2011 IGJPS. All rights reserved.

Key concepts: Bioadhesive, Mucoadhesion, Buccal administration, Drug delivery, Buccal mucosa, Drug, Pharmacology, Medicine

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