Comparison of serum calcium and 25-hydroxyvitamin D levels among pregnancies with gestational diabetes mellitues, impaired glucose tolerance and normal glucose tolerance

We aimed to assess the serum calcium and 25-hydroxyvitamin D levels among the pregnant who has gestational diabetes, impaired glucose tolerance and normal glucosetolerance. We included 151 pregnant who underwent oral glucose tolerance test between November 2014 and April 2015. Fasting blood glucose level, oral glucose tolerance test with 50 g of glucose and serum levels of 25-hydroxyvitamin D were performed to whom BMI was ≤30 at between 24-28 weeks of pregnancy. Patients with abnormal response to challenge test underwent standard 100 g, 3-hour oral glucose tolerance test (OGTT). There were three groups as follows: group 1 with impaired glucose tolerance, group 2 gestational diabetes mellitus and group 3 normal glucose levels. Serum levels of 25-hydroxyvitamin D did not demonstrate statistically significant difference between gestational diabetes mellitus, impaired glucose tolerance and normal glucose tolerance groups. There was no statistically significant difference in serum calcium levels between the groups. The main parity was statistically significantly higher in gestational diabetes mellitus group than impaired glucose tolerance and normal glucose tolerance groups. The fasting blood glucose levels of the control group were significantly lower than those of impaired glucose tolerance and gestational diabetes mellitus groups. We did not detect any significant difference between subjects with gestational diabetes, impaired glucose tolerance and normal glucose tolerance test results. Further extensive researches are required to determine the underlying mechanism.