When to use PUVA or NB-UVB in mycosis fungoides

Mycosis fungoides (MF) is a cutaneous T-cell lymphoma of unknown etiology that primarily affects the adult population. In early stages of the disease phototherapy is a major therapeutic option. At the time NB-UVB therapy in early stages IA-IB patchy and thin plaques offers advantages over PUVA, due to its better tolerance and fewer side effects, the PUVA therapy remains the choice to MF in thinner plaques. The maintenance therapy is posed that could be associated with higher accumulation of radiation without achieving prevents future lesions, being the history of relapse the main predisposing factor to present new lesions in the future.