Ipratropium Bromide And Salbutamol Inhalations In Asthma And Chronic Bronchitis

Twenty-four patients with obstructive airway disease consisting of 14 Asthmatics and 10 Chronic bronchitis were studied for the bronchodilator effects of inhaled Salbtamol (SAL) and Ipratropium Bromide (IPRA) both individually and in combination. The individual drugs and their combination all produced equally significant bronchodilation in asthmatics (p<0.05). The asthmatics aged more than 30 years, showed a significantly greater bronchodilator effect (p< 0.05) with ipratropium alone or in combination with salbutamol. In Chronic Bronchitics, ipratropium was significantly more effective (p<0.05) than salbutamol and the combination more so. There were no major side effects.