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2016•Unpublished venueRequires access

Zebrafish as a model organism for cardiovascular studies

Suneeta Narumanchi

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Abstract

Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality worldwide. There is a need for a model organism which is cost effective, easy to use and maintain in a lab. Zebrafish qualifies very well for all these criteria. The maintenance cost is much lower than rodents and it is a small animal and easy to use. Adult zebrafish grows to 3-4 cm and females can lay hundreds of eggs daily; providing a good supply of embryos for the experiments. The complete genome of the zebrafish is sequenced, making genetic modifications and related studies possible.

About this research paper

What this paper is about

Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality worldwide. There is a need for a model organism which is cost effective, easy to use and maintain in a lab. Zebrafish qualifies very well for all these criteria. The maintenance cost is much lower than rodents and it is a small animal and easy to use. Adult zebrafish grows to 3-4 cm and females can lay hundreds of eggs daily; providing a good supply of embryos for the experiments. The complete genome of the zebrafish is sequenced, making genetic modifications and related studies possible.

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Available abstract

Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality worldwide. There is a need for a model organism which is cost effective, easy to use and maintain in a lab. Zebrafish qualifies very well for all these criteria. The maintenance cost is much lower than rodents and it is a small animal and easy to use. Adult zebrafish grows to 3-4 cm and females can lay hundreds of eggs daily; providing a good supply of embryos for the experiments. The complete genome of the zebrafish is sequenced, making genetic modifications and related studies possible.

Key concepts: Zebrafish, Model organism, Organism, Animal model, Biology, Genetic model, Computational biology, Genome

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