2017•Gynecologic Oncology ReportsOpen access

Spontaneous regression of gestational trophoblastic neoplasia

Kaoru Niimi, Eiko Yamamoto, Kimihiro Nishino, Sawako Fujiwara, Kazuhiko Ino, Fumitaka Kikkawa

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Abstract

•We present two cases of postmolar gestational trophoblastic neoplasia (GTN).•Both cases presented with lung metastases after hydatidiform mole.•Both cases showed spontaneous regression without treatment.•The mechanism behind this phenomenon remains unclear.•Patients with postmolar GTN and declining hCG values may not need chemotherapy.

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What this paper is about

•We present two cases of postmolar gestational trophoblastic neoplasia (GTN).•Both cases presented with lung metastases after hydatidiform mole.•Both cases showed spontaneous regression without treatment.•The mechanism behind this phenomenon remains unclear.•Patients with postmolar GTN and declining hCG values may not need chemotherapy.

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Available abstract

•We present two cases of postmolar gestational trophoblastic neoplasia (GTN).•Both cases presented with lung metastases after hydatidiform mole.•Both cases showed spontaneous regression without treatment.•The mechanism behind this phenomenon remains unclear.•Patients with postmolar GTN and declining hCG values may not need chemotherapy.

Key concepts: Gestational trophoblastic neoplasia, Medicine, Trophoblastic neoplasm, Chemotherapy, Lung, Gestational age, Gestational trophoblastic disease, Choriocarcinoma

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