2013•DOAJ (DOAJ: Directory of Open Access Journals)Open access

Study of visual cortex of children amblyopia with blood oxygen level dependent-functional magnetic resonance imaging

Huifang Zhang, Zhen-Guo Yan, Bo Lin

Abstract

Blood oxygen level dependence-functional magnetic resonance imaging(BOLD-fMRI)utilizing the endogenous paramagnetic material-deoxygenated hemoglobin as a contrast agent gains signal changes of MRI in cortical intravascular and obtains images of the active area. Due to accurate location, intuitive and noninvasive, BOLD-fMRI is applied widely and provides objective evidence for amblyopia neurogenesis mechanism, ocular dominance column, motion perception and color vision.

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Available abstract

Key concepts: Blood-oxygen-level dependent, Functional magnetic resonance imaging, Visual cortex, Magnetic resonance imaging, Neuroscience, Nuclear magnetic resonance, Oxygen, Medicine