Evaluation Of Antiretroviral On HIV/AIDS Patients At 2012 -2013 Period In One Hospital In Bandung

HIV/AIDS is a chronic disease that develops progressively and uses antiretroviral drugs as the therapy. For an HIV-positive patient, antiretroviral therapy is a lifelong treatment. Therefore, an evaluation of antiretroviral drug use in hospitals should be conducted. The aim of this study is to obtain information about antiretroviral drug use profile and the accuracy of antiretroviral drug use in RSUD in Bandung during the period of 2012 to 2013. This study was performed using an observational method and retrospective approach. The use of antiretroviral drug was calculated by Anatomical Theraupetic Chemical/Defined Daily Dose (ATC/DDD) and Drug Utilization 90% (DU90%) method. The result showed that the use of antiretroviral drugs tended to increase from 301.66 into 350.04 DDD/1000 inhabitants (outpatient) and there were 3 antiretroviral drugs (nevirapin, efavirenz, and lamivudin) which included in DU90% segment during 2012-2013 period. There was a presumed drug interaction (10%) between antiretroviral drugs (nevirapine) for tuberculosis and 2% of antiretroviral duplication.