2012International Journal of Research in Pharmaceutical SciencesOpen access

Antimicrobial activity and phytochemical constituents of combined extracts of cissusquadrangularis and aegle marmelos

Prema Rathinam, K.B. Chandra Sekhar, D Satheesh Sekhar

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Abstract

This study is a part of a screening project has been dedicated to investigate the antimicrobial and phytochemical constituents of combined plant extracts. Antimicrobial activity and phytochemical constituents of ethanolic and ethylacetate extracts of Cissus quandrangularis (stem) and Aegle marmelos (fruit pulp) was investigated. The crude extracts were analysed for the presence of some phytochemical constituents. Phytochemical screening of the crude extracts revealed the presence of flavonoids, carbohydrates, cardiac glycosides, tannins, phenolic compounds, saponins, fat and oils, gums and mucillages and terpenoids. And the extracts were tested for antimicrobial activity against certain organisms such as Staphylococcus aureus, klebsiella pneumoniae, Escherichia coli and Bacillus subtillis. They showed significant antimicrobial activity against the above mentioned organisms. The zone of inhibition in mm was recorded. Since ancient ages plants have served human beings as a natural source of treatments and therapies amongst them medicinal herbs have gained attention because of its wide use and less side effects. The results lead to the conclusion that the combined extracts of Cissus quadrangularis and Aegle marmelos possesses effective antimicrobial activity.

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What this paper is about

This study is a part of a screening project has been dedicated to investigate the antimicrobial and phytochemical constituents of combined plant extracts. Antimicrobial activity and phytochemical constituents of ethanolic and ethylacetate extracts of Cissus quandrangularis (stem) and Aegle marmelos (fruit pulp) was investigated. The crude extracts were analysed for the presence of some phytochemical constituents. Phytochemical screening of the crude extracts revealed the presence of flavonoids, carbohydrates, cardiac glycosides, tannins, phenolic compounds, saponins, fat and oils, gums and mucillages and terpenoids. And the extracts were tested for antimicrobial activity against certain organisms such as Staphylococcus aureus, klebsiella pneumoniae, Escherichia coli and Bacillus subtillis. They showed significant antimicrobial activity against the above mentioned organisms. The zone of inhibition in mm was recorded. Since ancient ages plants have served human beings as a natural source of treatments and therapies amongst them medicinal herbs have gained attention because of its wide use and less side effects. The results lead to the conclusion that the combined extracts of Cissus quadrangularis and Aegle marmelos possesses effective antimicrobial activity.

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Available abstract

This study is a part of a screening project has been dedicated to investigate the antimicrobial and phytochemical constituents of combined plant extracts. Antimicrobial activity and phytochemical constituents of ethanolic and ethylacetate extracts of Cissus quandrangularis (stem) and Aegle marmelos (fruit pulp) was investigated. The crude extracts were analysed for the presence of some phytochemical constituents. Phytochemical screening of the crude extracts revealed the presence of flavonoids, carbohydrates, cardiac glycosides, tannins, phenolic compounds, saponins, fat and oils, gums and mucillages and terpenoids. And the extracts were tested for antimicrobial activity against certain organisms such as Staphylococcus aureus, klebsiella pneumoniae, Escherichia coli and Bacillus subtillis. They showed significant antimicrobial activity against the above mentioned organisms. The zone of inhibition in mm was recorded. Since ancient ages plants have served human beings as a natural source of treatments and therapies amongst them medicinal herbs have gained attention because of its wide use and less side effects. The results lead to the conclusion that the combined extracts of Cissus quadrangularis and Aegle marmelos possesses effective antimicrobial activity.

Key concepts: Phytochemical, Antimicrobial, Traditional medicine, Terpenoid, Klebsiella pneumoniae, Glycoside, Staphylococcus aureus, Biology

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