2017•Asian Journal of Medical SciencesOpen access

Association of hypokalemic periodic paralysis with cystic Kidney disease- A case report

Ricken Mehta, David Mathew Thomas, Vedavathi Ramakrishna, Sanjay Senaba Chikkananjaiah, Chandrashekhar Hosadurga Rudraswamy

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Abstract

Hypokalemic periodic paralysis (HPP) is a rare heterogenous neuromuscular disorder presenting with acute weakness. Though most cases are known to be familial or primary there are other underlying secondary causes which require evaluation and if not corrected could lead to recurrent episodes.Distal renal tubular acidosis (RTA) is one such association which has been described. Type 1/Distal RTA is known to cause renal potassium wasting thereby leading to hypokalemia. Patients with Distal RT A are unable to acidify their urine. The causes of Distal RTA can be hereditary, congenital, acquired or idiopathic. Severe hypokalemia with RTA has been described along with Medullary sponge Kidney and other cystic lesions in the kidney. There have been previous reports of hypokalemic paralysis occurring secondary to RT A precipitated by cystic kidney disease. We hereby report one such of hypokalemic periodic paralysis secondary to distal RTA which was associated with cystic kidney disease.Asian Journal of Medical Sciences Vol.8(4) 2017 57-59

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Hypokalemic periodic paralysis (HPP) is a rare heterogenous neuromuscular disorder presenting with acute weakness. Though most cases are known to be familial or primary there are other underlying secondary causes which require evaluation and if not corrected could lead to recurrent episodes.Distal renal tubular acidosis (RTA) is one such association which has been described. Type 1/Distal RTA is known to cause renal potassium wasting thereby leading to hypokalemia. Patients with Distal RT A are unable to acidify their urine. The causes of Distal RTA can be hereditary, congenital, acquired or idiopathic. Severe hypokalemia with RTA has been described along with Medullary sponge Kidney and other cystic lesions in the kidney. There have been previous reports of hypokalemic paralysis occurring secondary to RT A precipitated by cystic kidney disease. We hereby report one such of hypokalemic periodic paralysis secondary to distal RTA which was associated with cystic kidney disease.Asian Journal of Medical Sciences Vol.8(4) 2017 57-59

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Available abstract

Hypokalemic periodic paralysis (HPP) is a rare heterogenous neuromuscular disorder presenting with acute weakness. Though most cases are known to be familial or primary there are other underlying secondary causes which require evaluation and if not corrected could lead to recurrent episodes.Distal renal tubular acidosis (RTA) is one such association which has been described. Type 1/Distal RTA is known to cause renal potassium wasting thereby leading to hypokalemia. Patients with Distal RT A are unable to acidify their urine. The causes of Distal RTA can be hereditary, congenital, acquired or idiopathic. Severe hypokalemia with RTA has been described along with Medullary sponge Kidney and other cystic lesions in the kidney. There have been previous reports of hypokalemic paralysis occurring secondary to RT A precipitated by cystic kidney disease. We hereby report one such of hypokalemic periodic paralysis secondary to distal RTA which was associated with cystic kidney disease.Asian Journal of Medical Sciences Vol.8(4) 2017 57-59

Key concepts: Medicine, Hypokalemia, Renal tubular acidosis, Hypokalemic periodic paralysis, Distal renal tubular acidosis, Kidney, Pediatrics, Paralysis

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Association of hypokalemic periodic paralysis with cystic Kidney disease- A case report — Research Paper | ScholarLens