A COMPARATIVE STUDY OF PRE-INDUCTION ROCURONIUM WITH POST-INDUCTION SUCCINYLCHOLINE FOR RAPID SEQUENCE INTUBATION IN EMERGENCY SURGERIES

BACKGROUNDRapid Sequence Intubation (RSI) is the demand for emergency surgeries.Many investigators leveled Succinylcholine as the gold standard for the RSI intubation.But in most of those studies, both Succinylcholine and Rocuronium were used post-induction and the dose of Rocuronium varied.Hence, the present study is designed to compare the intubating condition achieved by preinduction Rocuronium 1 mg/ kg body weight vs. post-induction Succinylcholine 1.5 mg/kg body weight and to determine whether Rocuronium can be the suitable alternative to Succinylcholine in RSI intubation. MATERIALS AND METHODSThe study was designed, 1.To compare the intubating condition achieved by Rocuronium and Succinylcholine during rapid sequence intubation for emergency surgeries.2. To find out whether Rocuronium can be the suitable alternative to Succinylcholine.144 consenting patients of ASA-I and ASA-II of either sex and age group of 18 -45 yrs.were taken up for the study. RESULTSThere was no significant difference in intubation conditions achieved by either drug.Induction to vocal cord paralysis time was little shorter with succinylcholine than Rocuronium, but statistically insignificant.However, paralysis caused by Rocuronium lasted for longer extent of time (35 -52 mins.), whereas paralysis of Succinylcholine recovered spontaneously after 5 -10 mins. CONCLUSIONRocuronium may be recommended as an alternative to Succinylcholine if used pre-induction with 1 mg/kg BW for RSI intubation and advantageous for emergency surgeries of approximate one-hour duration or more.