A Second Look at Second-Look Endoscopy for Bleeding Peptic Ulcers

Data conflict on the value of routine repeat endoscopy after initial therapeutic endoscopy for managing peptic ulcer bleeding. Therefore, investigators randomized 194 patients with bleeding peptic ulcers and high-risk stigmata (active bleeding, visible vessel, or adherent clot) to undergo either repeat endoscopy and endoscopic therapy (with dilute epinephrine injection and thermal coagulation), if appropriate, 16-24 hours after initial hemostasis, or no endoscopic follow-up after initial endoscopic therapy. …