2016Journal of Pharmacognosy and PhytochemistryRequires access

Evaluation of anti-inflammatory activity of Trichosanthes dioica R. Leaves

Nitin Kumar, Sunil Kumar, Vijay Sharma, Anurag Chaudhary

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Abstract

Trichosanthes dioica R. (T. dioica) is an easily available common plant. The plant belongs to family Cucurbitaceae which has given us many important medicinal plants like Momordica charantia, Citrullus colocynthis etc. from which important pharmacological activities and markers like charantin and Cucurbitacin have been reported and isolated. In the present study T. dioica was evaluated for anti-inflammatory activity using carrageenan induced acute inflammation model in rats. It was concluded that leaves of T. dioica possess moderate anti-inflammatory activity.

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What this paper is about

Trichosanthes dioica R. (T. dioica) is an easily available common plant. The plant belongs to family Cucurbitaceae which has given us many important medicinal plants like Momordica charantia, Citrullus colocynthis etc. from which important pharmacological activities and markers like charantin and Cucurbitacin have been reported and isolated. In the present study T. dioica was evaluated for anti-inflammatory activity using carrageenan induced acute inflammation model in rats. It was concluded that leaves of T. dioica possess moderate anti-inflammatory activity.

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Available abstract

Trichosanthes dioica R. (T. dioica) is an easily available common plant. The plant belongs to family Cucurbitaceae which has given us many important medicinal plants like Momordica charantia, Citrullus colocynthis etc. from which important pharmacological activities and markers like charantin and Cucurbitacin have been reported and isolated. In the present study T. dioica was evaluated for anti-inflammatory activity using carrageenan induced acute inflammation model in rats. It was concluded that leaves of T. dioica possess moderate anti-inflammatory activity.

Key concepts: Trichosanthes, Cucurbitaceae, Citrullus colocynthis, Momordica, Urtica dioica, Traditional medicine, Anti-inflammatory, Carrageenan

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