(2,4-Dichlorophenyl)(3-hydroxypiperidin-1-yl)methanone: crystal structure and Hirshfeld analysis
U. Mohamooda Sumaya, D. Reuben Jonathan, Dravida Thendral Era, S. Gomathi, G. Usha
Abstract
Open-access reader
U. Mohamooda Sumaya, D. Reuben Jonathan, Dravida Thendral Era, S. Gomathi, G. Usha
Abstract
Open-access reader
In the title compound, C12H13Cl2NO2, the piperidine ring adopts a chair conformation. The dihedral angle between the mean plane of the piperidine ring and the benzene ring is 58.5 (3)°. In the crystal, molecules are linked by O—H...O hydrogen bonds, forming chains propagating along theb-axis direction. The chains are linked by C—H...O hydrogen bonds, forming undulating sheets parallel to theabplane. The C atoms of the hydroxypiperidine ring are disordered over two sets of sites with refined occupancies of 0.545 (7) and 0.455 (7). The intermolecular interactions in the crystal structure were quantified using Hirshfeld surface analysis.
OpenAlex reports 3 citations for this work. Citation counts describe recorded attention and do not establish research quality.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
In the title compound, C12H13Cl2NO2, the piperidine ring adopts a chair conformation. The dihedral angle between the mean plane of the piperidine ring and the benzene ring is 58.5 (3)°. In the crystal, molecules are linked by O—H...O hydrogen bonds, forming chains propagating along theb-axis direction. The chains are linked by C—H...O hydrogen bonds, forming undulating sheets parallel to theabplane. The C atoms of the hydroxypiperidine ring are disordered over two sets of sites with refined occupancies of 0.545 (7) and 0.455 (7). The intermolecular interactions in the crystal structure were quantified using Hirshfeld surface analysis.
Key concepts: Piperidine, Dihedral angle, Ring (chemistry), Chemistry, Crystal structure, Hydrogen bond, Crystallography, Intermolecular force