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2017•Sexually Transmitted InfectionsRequires access

Chlamydia trachomatis -induced reactive arthritis in India: frequency and clinical presentation

Praveen Kumar, Darshan Singh Bhakuni, Geetika Khanna, Sumit Batra, Vinod Sharma, Sangita Rastogi

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Abstract

Chlamydia trachomatis ( C. trachomatis )-induced reactive arthritis (ReA)/undifferentiated spondyloarthropathy (uSpA) are unrecognised/underestimated entities, and clinicians often fail to recognise them. In India, our group was the first to report intra-articular C. trachomatis infection in patients with ReA/uSpA having genitourinary symptoms.1 Males were predominant (78%) and majority of patients presented with an oligoarthritic profile (80%), enthesitis (11%) and human leukocyte antigen (HLA) B27 (40%); however, none reported ocular infection. Despite this observation, it is also very likely that C. trachomatis -induced ReA/uSpA is underdiagnosed in women. Intra-articular C. trachomatis …

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What this paper is about

Chlamydia trachomatis ( C. trachomatis )-induced reactive arthritis (ReA)/undifferentiated spondyloarthropathy (uSpA) are unrecognised/underestimated entities, and clinicians often fail to recognise them. In India, our group was the first to report intra-articular C. trachomatis infection in patients with ReA/uSpA having genitourinary symptoms.1 Males were predominant (78%) and majority of patients presented with an oligoarthritic profile (80%), enthesitis (11%) and human leukocyte antigen (HLA) B27 (40%); however, none reported ocular infection. Despite this observation, it is also very likely that C. trachomatis -induced ReA/uSpA is underdiagnosed in women. Intra-articular C. trachomatis …

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Available abstract

Chlamydia trachomatis ( C. trachomatis )-induced reactive arthritis (ReA)/undifferentiated spondyloarthropathy (uSpA) are unrecognised/underestimated entities, and clinicians often fail to recognise them. In India, our group was the first to report intra-articular C. trachomatis infection in patients with ReA/uSpA having genitourinary symptoms.1 Males were predominant (78%) and majority of patients presented with an oligoarthritic profile (80%), enthesitis (11%) and human leukocyte antigen (HLA) B27 (40%); however, none reported ocular infection. Despite this observation, it is also very likely that C. trachomatis -induced ReA/uSpA is underdiagnosed in women. Intra-articular C. trachomatis …

Key concepts: Chlamydia trachomatis, Reactive arthritis, Medicine, Spondyloarthropathy, HLA-B27, Chlamydiaceae, Chlamydiales, Immunology

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