Tissue plasminogen activator improved clinical outcome after acute ischemic stroke

TherapeuticsMay 1, 1996Tissue plasminogen activator improved clinical outcome after acute ischemic strokeWill Longstreth, MDWill Longstreth, MDHarborview Medical Center, Seattle, Washington, USA (W.L.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/ACPJC-1996-124-3-058 SectionsAboutFull Text ToolsAdd to favoritesDownload CitationsTrack Citations ShareFacebookTwitterLinkedInRedditEmail Source CitationThe National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995 Dec 14;333:1581-7.References1 Randomised controlled trial of streptokinase, aspirin, and combination of both in treatment of acute ischaemic stroke. Multicentre Acute Stroke Trial—Italy (MAST-I) Group. Lancet. 1995;346:1509-14. Google Scholar2 Major Ongoing Stroke Trials. Stroke. 1995;26:1978-82. Google Scholar3 Hacke W, Kaste M, Fieschi C, et al. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS). JAMA. 1995;274:1017-25. Google Scholar4 Duke RJ, Block RF, Turpie AG, Trebilcock R, Bayer N. Intravenous heparin for the prevention of stroke progression in acute partial stable stroke. Ann Intern Med. 1986;105:825-8. Google Scholar5 del Zoppo GJ. Acute stroke—on the threshold of a therapy? [Editorial]. N Engl J Med. 1995;333:1632-3. Google Scholar Author, Article, and Disclosure InformationAffiliations: Harborview Medical Center, Seattle, Washington, USA (W.L.) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails May 1, 1996Volume 124, Issue 3Page: 58KeywordsAnticoagulantsAttentionBlood pressureBody weightBrainClinical trialsDrugsEpileptic seizuresGastrointestinal tractGlucoseHemorrhageHeparinIschemic strokeMorbidityMyocardial infarctionPatientsPlateletsStrokeSurgeryTest statistics ePublished: 9 March 2020 Issue Published: May 1, 1996 Copyright & PermissionsCopyright © 1996 by American College of Physicians. All Rights Reserved.Loading ...