2012Journal of chemical and pharmaceutical researchRequires access

The synthesis of (Z)-5-(2,2-diethoxyethylidene)-4-methylfuran-2(5H)-one

Noureddine Tamma, Noureddine Gherraf, Abdelghani Hoggui

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Abstract

Butenolides are a class of lactones with a four carbon heterocyclic ring structure. They are sometimes considered as oxidized derivatives of furan. The simplest butenolide is 2-furanone, which is a common component of larger natural products and is sometimes referred to as simply butenolide. A common biochemically important butenolide is ascorbic acid (vitamin C). The butenolide and their analogues represent a wide range of the natural compounds of medical and biological importance. In the last decades, a great number of compounds of various structures, in general from Alkylidene butenolide were isolated and showed biological activities.In this work we have studied the reactivity of some alkylidene butenolide and carried out their antibacterial activity.

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Butenolides are a class of lactones with a four carbon heterocyclic ring structure. They are sometimes considered as oxidized derivatives of furan. The simplest butenolide is 2-furanone, which is a common component of larger natural products and is sometimes referred to as simply butenolide. A common biochemically important butenolide is ascorbic acid (vitamin C). The butenolide and their analogues represent a wide range of the natural compounds of medical and biological importance. In the last decades, a great number of compounds of various structures, in general from Alkylidene butenolide were isolated and showed biological activities.In this work we have studied the reactivity of some alkylidene butenolide and carried out their antibacterial activity.

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Available abstract

Butenolides are a class of lactones with a four carbon heterocyclic ring structure. They are sometimes considered as oxidized derivatives of furan. The simplest butenolide is 2-furanone, which is a common component of larger natural products and is sometimes referred to as simply butenolide. A common biochemically important butenolide is ascorbic acid (vitamin C). The butenolide and their analogues represent a wide range of the natural compounds of medical and biological importance. In the last decades, a great number of compounds of various structures, in general from Alkylidene butenolide were isolated and showed biological activities.In this work we have studied the reactivity of some alkylidene butenolide and carried out their antibacterial activity.

Key concepts: Butenolide, Ascorbic acid, Chemistry, Furan, Ring (chemistry), Reactivity (psychology), Stereochemistry, Organic chemistry

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The synthesis of (Z)-5-(2,2-diethoxyethylidene)-4-methylfuran-2(5H)-one — Research Paper | ScholarLens