2017•Journal of Pharmaceutical SciencesRequires access

Possibility of Predicting Serotonin Transporter Occupancy From the In Vitro Inhibition Constant for Serotonin Transporter, the Clinically Relevant Plasma Concentration of Unbound Drugs, and Their Profiles for Substrates of Transporters

Masahiro Yahata, Kōji Chiba, Takao Watanabe, Yuichi Sugiyama

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Key concepts: Serotonin transporter, Norepinephrine transporter, Transporter, Serotonin Plasma Membrane Transport Proteins, Reuptake, In vivo, Pharmacology, Chemistry

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Possibility of Predicting Serotonin Transporter Occupancy From the In Vitro Inhibition Constant for Serotonin Transporter, the Clinically Relevant Plasma Concentration of Unbound Drugs, and Their Profiles for Substrates of Transporters — Research Paper | ScholarLens