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Morphological Patterns of the Placenta Remodelling In Cases of IUGR at 20-25 Weeks of Gestation
I. Gorianikova, Olga Kononenko, O. Teleshova
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Abstract
Introduction/ Background Placental insufficiency is an important factor of the fetal intrauterine growth restriction (IUGR). Aims To confirm the relation between placental morphology changes and fetal IUGR 20 placentas in cases of IUGR at 20-25 weeks of gestation (wg) were compared with 20 placentas at the same wg but without fetal IUGR . Methods Material was divided: 10 placentas at 20-22wg and 10 – at 23-25wg both in cases of IUGR, which were studied with corresponding 10 (20-22wg) and 10 (23-25wg) controls. Volume fractions (vf) of the major placental components were determined from 5mmk paraffin sections. Results The results have shown that both placental and fetal weights in IUGR groups were smaller than in controls. The poor vascularisation and immaturity of the villous tree were found in cases of IUGR. The thickness of placental membrane increased from 10.74±0.09 at 20-22wg and 10.92±0.09 at 23-25wg in controls to 11.62±0.1 and 11.87±0.12mmk, p
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