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2017•Cardiovascular Innovations and ApplicationsOpen access

Antithrombotic Therapy: Focus on the Elderly

Jingwei Zhang, Meilin Liu

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Abstract

Advanced age brings a higher incidence of thrombosis-related diseases. Although antithrombotic therapy significantly reduces the risk of ischemic events, relatively higher bleeding rates result in increased mortality and worse prognosis in the elderly. Thus the benefits and harms of antithrombotic drugs should to be carefully evaluated. In this review, we summarize current evidence and updated guidelines regarding antithrombotic therapy in the aging population.

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What this paper is about

Advanced age brings a higher incidence of thrombosis-related diseases. Although antithrombotic therapy significantly reduces the risk of ischemic events, relatively higher bleeding rates result in increased mortality and worse prognosis in the elderly. Thus the benefits and harms of antithrombotic drugs should to be carefully evaluated. In this review, we summarize current evidence and updated guidelines regarding antithrombotic therapy in the aging population.

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Available abstract

Advanced age brings a higher incidence of thrombosis-related diseases. Although antithrombotic therapy significantly reduces the risk of ischemic events, relatively higher bleeding rates result in increased mortality and worse prognosis in the elderly. Thus the benefits and harms of antithrombotic drugs should to be carefully evaluated. In this review, we summarize current evidence and updated guidelines regarding antithrombotic therapy in the aging population.

Key concepts: Antithrombotic, Medicine, Thrombosis, Incidence (geometry), Intensive care medicine, Fibrinolytic agent, Population, Internal medicine

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