2016•The Indian Journal of Medical ResearchOpen access

Correlation of cartilage metabolic markers & antioxidants with the severity of knee osteoarthritis

Sonam Choden Bhutia, Mingma Sherpa, S K Dewan, T. A. Singh

Abstract

Osteoarthritis is characterized by the degeneration of articular cartilage. Cartilage metabolic markers have been explored as possible markers for osteoarthritis, and osteogenic protein -1 (OP-1) has emerged out to play a major role in cartilage repair. Oxidative stress has been implicated as a mediator of cartilage damage in patients with osteoarthritis. The aim of this study was to correlate the cartilage metabolic markers and antioxidants with the severity of knee osteoarthritis.

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Key concepts: Osteoarthritis, Cartilage, Articular cartilage, Medicine, Oxidative stress, Cartilage damage, Articular cartilage damage, Degeneration (medical)