2017•Clinical Pharmacology & TherapeuticsRequires access

Electronic Medical Record‐Integrated Pharmacogenomics and Related Clinical Decision Support Concepts

Pedro J. Caraballo, Suzette J. Bielinski, Jennifer L. St. Sauver, Richard M. Weinshilboum

Abstract

Advances in pharmacogenomics (PGx) have the potential to transform healthcare by allowing precision medicine to become a reality. However, PGx knowledge is new, complex, and evolving, and relying on the cognition of clinicians alone is insufficient for clinical implementation. Integrating clinical decision support (CDS) tools in the electronic health record (EHR) is critical for translating PGx into clinical practice. Herein, we review current strategies to implement PGx using EHR-CDS functionalities.

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Key concepts: Pharmacogenomics, Clinical decision support system, Electronic health record, Electronic medical record, Precision medicine, Decision support system, Clinical decision making, Health records