2017Journal of NeuroscienceOpen access

Gpr126 Is Critical for Schwann Cell Function during Peripheral Nerve Regeneration

Corey Fernandez, Manasi Iyer, Isabel I. C. Low

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Abstract

Unlike their counterparts in the CNS, neurons in the peripheral nervous system (PNS) display a remarkable regenerative capacity following injury largely due to Schwann cell (SC) activity, which provides critical support for growth and repair ([Fig. 1][1]). After injury (e.g., when the axon is cut or

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Unlike their counterparts in the CNS, neurons in the peripheral nervous system (PNS) display a remarkable regenerative capacity following injury largely due to Schwann cell (SC) activity, which provides critical support for growth and repair ([Fig. 1][1]). After injury (e.g., when the axon is cut or

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Available abstract

Unlike their counterparts in the CNS, neurons in the peripheral nervous system (PNS) display a remarkable regenerative capacity following injury largely due to Schwann cell (SC) activity, which provides critical support for growth and repair ([Fig. 1][1]). After injury (e.g., when the axon is cut or

Key concepts: Schwann cell, Regeneration (biology), Axon, Peripheral nervous system, Neuroscience, Peripheral nerve injury, Peripheral nerve, Peripheral

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