2009•Unpublished venueRequires access
Colicin E1 production is associated with bacteriocinmultiproducer strains in uropathogenic Escherichia coli.
David Šmajs, Lenka Micenková, Jan Šmarda, M Vrba, Anna Ševčíková, Zuzana Vališová, Vladana Woznicová
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Abstract
The incidence of 29 bacteriocin types were tested in a group of
377 E. coli strains isolated from urinary tract infections
(UTI) and in 413 control strains isolated from feces of
patients without bacterial gut infection. The spectrum and
frequency of individual bacteriocin types in the UTI strains
was very similar to the control strains, probably reflecting
the origin of UTI strains in the human gut. In the group of E.
coli UTI strains, 159 bacteriocin producing strains (42.2%)
were identified being not significantly different from 199
bacteriocin producers in the control group (48.2%). Producers
with 3 and more identified bacteriocin types were more frequent
in the UTI group. In the UTI strains, there is a marked
increase of strains producing colicin E1 when compared to
control (14.3% and 6.8%, respectively, p = 0.002). Moreover,
this tendency is associated with multiproducers. There is a
tendency in the UTI strains to possess additional genetic
determinants and to synthesize colicin E1.