Tiagabine treatment for epilepsy spares eyesight

Aims: To evaluate angiographic features of myopic crescents using fluorescein angiography (FA) and indocyanine green angiography (IA).Methods: FA and IA angiograms of 88 highly myopic eyes (47 consecutive patients) were reviewed.The follow up period ranged from 5-28 years.Results: FA revealed two zones of the myopic crescent: a consistently hypofluorescent inner zone and an outer zone with delayed choroidal filling.IA revealed dislocation of the Zinn-Haller ring to the border between the two zones.Myopic crescent enlargement occurred in 68.1%.Only the outer zone increased significantly in most of the eyes with enlarged crescents.Conclusions: The inner zone might develop as a result of mechanical stretching, and the outer zone might be the result a secondary circulatory disturbance and mechanical stretching.