Haematopoietic effect of ethanolic leaf extract of Piliostigma thonningii onmale albino rat

This research was an attempt to provide an ameliorative measure for patients with haematological disorders by considering the effect of ethanol leaf extract of P. thonningii on some haematological parameters of male albino wistar rats. Twenty (20) male albino Wistar rats were randomly assigned on the basis of average body weight into four (4) groups of five (5) rats each. While group A served as the control and received distilled water of treatment equivalence, group B, C and D were administered with 50,100 and 200mg/kg body weight of the extract respectively via oral gavages and treatment lasted for twenty-one (21) days. The extract produced a significant (p< 0.05) increase on white blood cells (WBC), and Monocytes at various dosages administered. However, a significant (p< 0.05) decreased was recorded for neutrophils. The red blood cells (RBC), packed cell volume (PCV), haemoglobin (HB), lymphocytes and platelets levels all recorded a significant (p< 0.05) increase at 100, and 200mg/kg body weight. Sequel to results, the ethanolic extract of P. thonningii appears to possess haematopoietic potentials.