Genetic pattern of cystic fibrosis patients in Azeri Turkish population
Morteza Jabarpoor-Bonyadi, Mandana Rafeey, Amir Vahedi, Leila Vahedi
Abstract
Morteza Jabarpoor-Bonyadi, Mandana Rafeey, Amir Vahedi, Leila Vahedi
Abstract
Introduction Cystic fibrosis (CF; OMIM 219700) is the most common lethal autosomal recessive disorder that involving some organs as the bronco pulmonary, gastrointestinal reproductive systems, and sweat glands [1-3]. Mutations on the cystic fibrosis transmembrane conductance regulator (CFTR) gene on chromosome 7q31.2 result in this disease [4]. The incidence of CF in Middle
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Introduction Cystic fibrosis (CF; OMIM 219700) is the most common lethal autosomal recessive disorder that involving some organs as the bronco pulmonary, gastrointestinal reproductive systems, and sweat glands [1-3]. Mutations on the cystic fibrosis transmembrane conductance regulator (CFTR) gene on chromosome 7q31.2 result in this disease [4]. The incidence of CF in Middle
Key concepts: Turkish population, ΔF508, Cystic fibrosis, Genotype, Medicine, Cystic fibrosis transmembrane conductance regulator, Consanguinity, Population