2017•European Journal of RheumatologyOpen access

Pauci-immune lupus nephritis: possibility or co-incidence?

Döndü Üsküdar Cansu, Gökhan Temïz, Mustafa Fuat Açıkalın, Cengiz Korkmaz

Abstract

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized with immune complex formation and renal involvement of lupus and may include several kinds of pathological conditions, but mostly, it is associated with immune complex-induced glomerular disease. Pauci-immune lupus nephritis is a very rare condition. We describe a 45-year-old female patient with pauci-immune crescentic necrotizing lupus nephritis and briefly discuss the possible mechanism and pathogenesis.

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Key concepts: Lupus nephritis, Medicine, Immune system, Immune complex, Immunology, Pathogenesis, Systemic lupus erythematosus, Pathological