2017•Bioorganic & Medicinal ChemistryOpen access

Synthesis of conformationally restricted 1,3-dioxanes to analyze the bioactive conformation of 1,3-dioxane-based σ1 and PCP receptor antagonists

Samuel Asare-Nkansah, Dirk Schepmann, Bernhard Wünsch

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Key concepts: Moiety, Chemistry, Stereochemistry, Substituent, Intramolecular force, Benzylamine, Methylene, Selectivity

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Synthesis of conformationally restricted 1,3-dioxanes to analyze the bioactive conformation of 1,3-dioxane-based σ1 and PCP receptor antagonists — Research Paper | ScholarLens