ScholarLens Back to search
2016•Bio-Medical Materials and EngineeringRequires access

Numerical modeling of vessel geometry to measure hemodynamics parameters non-invasively in cerebral arteriovenous malformation

Y. Kiran Kumar, Shashi Bhushan Mehta, Manjunath Ramachandra

Open publisher page 3 citations

Abstract

Cerebral arteriovenous malformations (CAVM) are congenital lesions that contain a cluster of multiple arteriovenous shunts (NIDUS). Cardiac arrhythmia in CAVM patients causes irregular changes in blood flow and pressure in the NIDUS area. This paper proposes the framework for creating the lumped model of tortuous vessel structure near NIDUS based on radiological images. This lumped model is to analyze flow variations, with various combinations of the transient electrical signals, which simulate similar conditions of cardiac arrhythmia in CAVM patients. This results in flow variation at different nodes of the lumped model. Here we present two AVM patients with evaluation of 150 vessels locations as node points, with an accuracy of 93%, the sensitivity of 95%, and specificity of 94%. The calculated p-value is smaller than the significance level of 0.05.

About this research paper

What this paper is about

Cerebral arteriovenous malformations (CAVM) are congenital lesions that contain a cluster of multiple arteriovenous shunts (NIDUS). Cardiac arrhythmia in CAVM patients causes irregular changes in blood flow and pressure in the NIDUS area. This paper proposes the framework for creating the lumped model of tortuous vessel structure near NIDUS based on radiological images. This lumped model is to analyze flow variations, with various combinations of the transient electrical signals, which simulate similar conditions of cardiac arrhythmia in CAVM patients. This results in flow variation at different nodes of the lumped model. Here we present two AVM patients with evaluation of 150 vessels locations as node points, with an accuracy of 93%, the sensitivity of 95%, and specificity of 94%. The calculated p-value is smaller than the significance level of 0.05.

Why it matters

OpenAlex reports 3 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Cerebral arteriovenous malformations (CAVM) are congenital lesions that contain a cluster of multiple arteriovenous shunts (NIDUS). Cardiac arrhythmia in CAVM patients causes irregular changes in blood flow and pressure in the NIDUS area. This paper proposes the framework for creating the lumped model of tortuous vessel structure near NIDUS based on radiological images. This lumped model is to analyze flow variations, with various combinations of the transient electrical signals, which simulate similar conditions of cardiac arrhythmia in CAVM patients. This results in flow variation at different nodes of the lumped model. Here we present two AVM patients with evaluation of 150 vessels locations as node points, with an accuracy of 93%, the sensitivity of 95%, and specificity of 94%. The calculated p-value is smaller than the significance level of 0.05.

Key concepts: Hemodynamics, Blood flow, Cardiology, Arteriovenous malformation, Cardiac cycle, Medicine, Sensitivity (control systems), Flow (mathematics)

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Numerical modeling of vessel geometry to measure hemodynamics parameters non-invasively in cerebral arteriovenous malformation — Research Paper | ScholarLens