Observation of the Serum Uric Acid in Essential Hypertension

In order to observe the relationship of hyperuricemia and essential hypertension, we studied serum uric acid in 139 patients with essential hypertension visiting the Department of Internal Medicine, Pusan National University Hospital, between May 1982 and July 1983, and analyzed its values in terms of various clinical and laboratory parameters. The mean concentration of serum uric acid and incidence of hyperuricemia in essential hypertension were 6.60 ± 1.96 mg%, 57.9% and those of the normal control group were 3.87 ± 1.30 mg%, 17.8%, respectively with significantly higher values in the hypertension group. The mean concentration of serum uric acid and the incidence of hyperuricemia were significantly correlated with the levels of diastolic blood pressure, mean arterial pressure, BUN, and serum creatinine. Significant correlation between the mean concentration of serum uric acid and the extent of target organ damage and abnormal urine findings were observed.