2006Chongqing Shifan Daxue xuebao. Ziran kexue banRequires access

Endothelial Progenitor Cells

Zhao Ying

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Abstract

during embryogenesis,endothelial progenitor cells participate in the initial processes of primitive blood vessel formation.It becomes evidently that endothelial progenitor cells are involved in postnatal reendothelization and vasculogenesis.It is suggested that endothelial progenitor cells will have clinical application prospects in vascular regeneration and treatment of heart and vascular diseases.Currently,there is no uniform definition of EPC,it was primarily defined by expression of cell surface antigens CD34、CD133、FLK-1.under steady-state physiological condition,quantity of EPCs is very low.In this review,we sum up pareiculary on phenotype,identification,isolation and culture and quantity of EPCs.

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during embryogenesis,endothelial progenitor cells participate in the initial processes of primitive blood vessel formation.It becomes evidently that endothelial progenitor cells are involved in postnatal reendothelization and vasculogenesis.It is suggested that endothelial progenitor cells will have clinical application prospects in vascular regeneration and treatment of heart and vascular diseases.Currently,there is no uniform definition of EPC,it was primarily defined by expression of cell surface antigens CD34、CD133、FLK-1.under steady-state physiological condition,quantity of EPCs is very low.In this review,we sum up pareiculary on phenotype,identification,isolation and culture and quantity of EPCs.

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Available abstract

during embryogenesis,endothelial progenitor cells participate in the initial processes of primitive blood vessel formation.It becomes evidently that endothelial progenitor cells are involved in postnatal reendothelization and vasculogenesis.It is suggested that endothelial progenitor cells will have clinical application prospects in vascular regeneration and treatment of heart and vascular diseases.Currently,there is no uniform definition of EPC,it was primarily defined by expression of cell surface antigens CD34、CD133、FLK-1.under steady-state physiological condition,quantity of EPCs is very low.In this review,we sum up pareiculary on phenotype,identification,isolation and culture and quantity of EPCs.

Key concepts: Vasculogenesis, Progenitor cell, Progenitor, Cell biology, Endothelial stem cell, CD34, Endothelial progenitor cell, Biology

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