Pathogenesis and Immune Responses in Newborn African Green Monkeys (Cercopithecus aethiops) Inoculated with Simian Immunodeficiency Virus (SIVagm)

Simian immunodeficiency viruses (SIVs) are diverse group of viruses that naturally infect a wide range of African primates, including African Green Monkeys (AGMs). It has been shown that in vivo passage of SIV in rhesus macaque results in selection of pathogenic virus that causes Simian Acquired Immunodeficiency Syndrome.