2012•Zhonghua neifenmi daixie zazhiRequires access

Relationship between serum uric acid and nonalcoholic fatty liver in patients with type 2 diabetes

Mingzhen Li, Jiu-ying Hao, Sun Li-rong

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Abstract

A total of 1 007 inpatients with type 2 diabetes mellitus (T2DM) were divided into 2 groups,according to whether there was accompanied with nonalcoholic fatty liver(NAFLD) ; and the data of the two groups were analysed.Serum uric acid levels were positively correlated with body mass index and blood urea nitrogen and creatinine,while negatively correlated with HbA1c.T2DM patients complicated with NAFLD were younger,had shorter duration of T2DM,and showed impaired uric acid clearance with raised serum uric acid.The prevalence of NAFLD was higher with increasing serum uric acid levels. Key words: Nonalcoholic fatty liver; Diabetes mellitus; type 2; Serum uric acid

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What this paper is about

A total of 1 007 inpatients with type 2 diabetes mellitus (T2DM) were divided into 2 groups,according to whether there was accompanied with nonalcoholic fatty liver(NAFLD) ; and the data of the two groups were analysed.Serum uric acid levels were positively correlated with body mass index and blood urea nitrogen and creatinine,while negatively correlated with HbA1c.T2DM patients complicated with NAFLD were younger,had shorter duration of T2DM,and showed impaired uric acid clearance with raised serum uric acid.The prevalence of NAFLD was higher with increasing serum uric acid levels. Key words: Nonalcoholic fatty liver; Diabetes mellitus; type 2; Serum uric acid

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Available abstract

A total of 1 007 inpatients with type 2 diabetes mellitus (T2DM) were divided into 2 groups,according to whether there was accompanied with nonalcoholic fatty liver(NAFLD) ; and the data of the two groups were analysed.Serum uric acid levels were positively correlated with body mass index and blood urea nitrogen and creatinine,while negatively correlated with HbA1c.T2DM patients complicated with NAFLD were younger,had shorter duration of T2DM,and showed impaired uric acid clearance with raised serum uric acid.The prevalence of NAFLD was higher with increasing serum uric acid levels. Key words: Nonalcoholic fatty liver; Diabetes mellitus; type 2; Serum uric acid

Key concepts: Internal medicine, Uric acid, Endocrinology, Nonalcoholic fatty liver disease, Creatinine, Medicine, Diabetes mellitus, Type 2 Diabetes Mellitus

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