2008•Guoji shengwu yixue gongcheng zazhiRequires access

Effect and it's mechanism of microgravity on biological characteristics of hematopoietic stem/progenitor cells

Liu Ying-zheng, Zheng Lei, Qian Wang

Abstract

Hematopoietic stem/progenitor cells have the potential of self-renewal,proliferation and multidirectional differentiation,which maintain the normal haematopoiesis of bnmml body.Alterations in the number and function of mature blood cells in the peripheral blood commonly observed in humans exposed to microgravity (μ-g)are results of many reasons.The change of biological characteristic of hematopoietic stem/progenitor cells is one of the important ressons.Migration,proliferation,and differentiation of hematopoietic stem/progenitor cells under microgravity are summarized in this article. Key words: Microgravity; Hematopoietic stem/progenitor cell; Biological characteristics

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Key concepts: Haematopoiesis, Progenitor cell, Stem cell, Cell biology, Progenitor, Biology, Endothelial stem cell, Immunology