Peptide coating applied on the spot improves osseointegration of titanium implants
Anna Gitelman Povimonsky, Hanna Rapaport
Abstract
Anna Gitelman Povimonsky, Hanna Rapaport
Abstract
. In the model blood serum the peptide coated implants were found to adsorb cell adhesion proteins. The efficacy of peptide coated titanium alloy (Ti6Al4V) implants was tested in a rabbit femur bone model. Histology and micro-computerized tomography (μCT) analysis of the removed femora showed a higher bone density and improved bone-implant osseointegration compared to uncoated implants.
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. In the model blood serum the peptide coated implants were found to adsorb cell adhesion proteins. The efficacy of peptide coated titanium alloy (Ti6Al4V) implants was tested in a rabbit femur bone model. Histology and micro-computerized tomography (μCT) analysis of the removed femora showed a higher bone density and improved bone-implant osseointegration compared to uncoated implants.
Key concepts: Coating, Osseointegration, Titanium, Materials science, Biomedical engineering, Composite material, Implant, Metallurgy