Biochemical Studies of Alcohol Induced Liver Injury
Upma Agarwal, Ritu Sharma, Dinesh K Kansal
Abstract
Upma Agarwal, Ritu Sharma, Dinesh K Kansal
Abstract
Liver damage is one of the most common consequences of alcohol abuse but despite of an enormous amount of research efforts, the mechanism by which alcohol causes alcoholic liver diseases remains unknown. Evidence that association is independent of both alcohol consumption and changes in other liver function tests suggest that possible mechanisms beyond alcohol neurotoxicity and hepatic dysfunction deserve further investigation (Michael 1989) The present study was envisioned to carry out Biochemical studies of alcohol induced liver injury in the alcoholic patient with following aims and objects. i. To determine the effect of alcohol on liver function ii. To know effect of alcohol on lipid profile. iii. To know the quantity, quality and duration of alcohol intake in relation to liver damage and change in lipid metabolism. iv. To observe the effect of diet in liver damage in alcoholic.
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Liver damage is one of the most common consequences of alcohol abuse but despite of an enormous amount of research efforts, the mechanism by which alcohol causes alcoholic liver diseases remains unknown. Evidence that association is independent of both alcohol consumption and changes in other liver function tests suggest that possible mechanisms beyond alcohol neurotoxicity and hepatic dysfunction deserve further investigation (Michael 1989) The present study was envisioned to carry out Biochemical studies of alcohol induced liver injury in the alcoholic patient with following aims and objects. i. To determine the effect of alcohol on liver function ii. To know effect of alcohol on lipid profile. iii. To know the quantity, quality and duration of alcohol intake in relation to liver damage and change in lipid metabolism. iv. To observe the effect of diet in liver damage in alcoholic.
Key concepts: Alcohol, Liver injury, Ethanol, Medicine, Liver function, Alcohol consumption, Liver damage, Alcohol abuse